Asif Jamil

 me@asif.cc

Systems Neuroscientist | Neurotechnology | Clinical Translation
What I Work On I study how non-invasive brain stimulation interacts with intrinsic brain dynamics to produce adaptive or maladaptive plasticity, with an emphasis on translational neuropsychiatry.
Human neuromodulation - Device development

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I'm a research scientist and Principal Investigator in the Division of Neuropsychiatry and Interventional Psychiatry at Massachusetts General Hospital and Harvard Medical School. My research focuses on developing and optimizing non-invasive neuromodulation techniques to understand human neurophysiology and advance treatments for neuropsychiatric disorders.

Education, Training & Work

2011
BS, Biology
University of Maryland, College Park, USA
2012
MS, Neuroimaging
King's College London, UK
2017
PhD, Neuroscience
University of Göttingen, Germany
2017–2020
Postdoctoral Research Fellow
Leibniz Research Institute for Working Environment and Human Factors, Dortmund, Germany
2020–2021
Postdoctoral Research Fellow
Mass. General Hospital & Harvard Medical School, Boston, USA
2021–present
Instructor in Psychiatry
Mass. General Hospital & Harvard Medical School, Boston, USA

Research Areas

Establishing EEG-Based Biomarkers of Clinical Response Using Machine Learning

Building upon mechanistic neuromodulation work, I have developed a translational research program identifying EEG-based biomarkers and machine-learning predictors for clinical symptomology and neuromodulation response. My ongoing work involves building computational neuroimaging processing pipelines for ongoing neuromodulation clinical trials in major depression (MDD), ADHD, OCD, Alzheimer's Disease, and substance-use disorders (SUDs). Recent findings have identified reproducible EEG signatures associated with clinical symptoms, supporting the feasibility of data-driven precision neuromodulation wherein quantitative EEG metrics guide parameter selection.

Key Publications:

Characterizing Nonlinear Dose-Response Relationships and Mechanistic Principles of Human Neuroplasticity

Nonlinear neuroplasticity in human brain stimulation.

  • Dose-dependent reversals in stimulation after-effects across intensity and duration.
  • Polarity-specific modulation of cortical excitability and physiological biomarkers.
  • Multimodal validation with TMS-EEG and fMRI perfusion measures.
Key Publications:

Development of Temporally-Precise, Phase-Synchronized rTMS+tACS Neuromodulation

Phase-synchronized rTMS+tACS to stabilize intrinsic brain rhythms.

  • Phase-locked stimulation protocols tuned to endogenous oscillations.
  • Targeted anatomical modeling and bespoke electrical/software systems.
  • Demonstrated functional gains in executive function and working memory.
Key Publications:

Translating Neuromodulation to Aging, Motor Learning, and Cognitive Rehabilitation

Translation of mechanistic neuromodulation to aging and rehabilitation.

  • Improved visuo-motor and bimanual control in healthy aging cohorts.
  • Intervention studies demonstrating robust motor-learning gains.
  • Pathway to practical rehabilitation protocols and clinical translation.
Key Publications:

Recent Talks & Lectures

Publications

Complete List on Pubmed

Complete List on Google Scholar